Advanced Task Killer Free - I used this more when I first got my phone, but after a while I have begun to realize that it really does not make that big of a difference in the overall performance of the phone. I still give this a go every once and a while when it starts to feel kludgy.<-- I am now using ES Task manager for this.- Amazon - never used...
 - Astrid - I use this all of the time with an online service that I thought I wouldn't like but have come to love RTM
 - Barcode Scanner - I have used this a handfull of times and it works well. I even used it at a big box store to look up a price. It found their website and tada...
 - ConnectBot - used for remote ssh sessions
 - Detexify - draw with your finger on the screen and it gives you the LaTeX code for it.
 - DockRunner - because I did't want to spend $30 on the charging dock.
 - DroidLight - I use this at least twice a day!
 - ES File Explorer - tool that I don't use often but is a must have when you need it.
 - ES Task Manager - I use this to close down programs that are running in the background. One of the flaws of the Android platform as I see it, is that there is not a clear way to close a program as opposed to having it run in the background.
 - GDocs - I hope to use this more as I move away from using MS office
 - Gmote
 - Goggles - cool concept but not very useful
 - Google Sky Map - again cool but...
 - gStrings - program for tuning a guitar, but I assume that it could be used for any musical instrument.
 - Google Voice - very nice
 - GTalk Updater - wish I didn't have it
 - IP Cam Viewer Lite - used for nanny cams when we are out
 IP Machine- Key Ring - keep my vic card and such on it, and my wallet it thiner. Now I don't even get odd looks from the cashiers anymore as I am guessing more people are using them.
 - Labyrinth Lite - I found this after my family was talking about the old game at christmas. Even my grandmother enjoyed this game.
 - Listen - used on the bus to listen to npr stuff.
 Locale - handy for making sure my ringer is turned off and such<-- No longer free and I don't feel like it is worth the $10 that they want for it now.GPS Plug-inSync Plug-inTweet Plug-in- Maps - has the navigation that has been useful running around town
 - Maverick Lite - cool, but unused as a compas
 - Metal Detector - fun party trick
 - MountUSB - used for adding music to droid
 - My Tracks - cool for tracking exercise distances
 NetCounterNetTools- OpenSudoku - fun
 - Orienteer - allows to see raw GPS data
 - OurGroceries - my wife has the iPhone/iPod version and this makes shopping a lot easier
 - Pandora - I only use on wifi, but I love Pandora radio
 - Photoshop.com Mobile - only used once, but it works
 - Pkt Auctions eBay - might use more if I wasn't broke
 - Places Directory - used to find food while traveling
 - Power Save - nice widget that provides the same functions that are built into 2.1
 - RTM - the official app for the RTM website, it is a pay service (yearly) but I am starting to think that it is worth it. Their to do list is fantastic, by far the best I have ever seen.
 - The Weather Channel - check for dress every morning
 - Twidroid - used all the time.
 - Whack-A-Droid
 
I am making this list for my own reference as I am going to unlock the phone and load the nexus one rom to it.  I will add a post to update on how that goes.